Vitamin B12 - Revision history

DefunctSprout: /* Diagnosis */ Shortened disclaimer and reworded.

2024-04-08T13:57:46Z

Diagnosis: Shortened disclaimer and reworded.

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	'''~~Whilst you may be tempted to~~ begin taking Vitamin B12 supplements when experiencing symptoms like ~~brain fog, it's important not to self-medicate without a confirmed diagnosis~~. Supplementing without doctor guidance can mask a deficiency by showing a falsely elevated test value, complicating the diagnosis and delaying the discovery of underlying health issues.'''		'''You should not begin taking Vitamin B12 supplements when experiencing symptoms like brainfog. Supplementing without doctor guidance can mask a deficiency by showing a falsely elevated test value, complicating the diagnosis and delaying the discovery of underlying health issues.'''

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DefunctSprout: /* See Also */ Renamed source for accuracy

2024-04-08T13:55:35Z

DefunctSprout: /* See Also */ Added source.

2024-04-08T13:54:52Z

DefunctSprout: /* B12 Toxicity */ Reworked 'B12 Toxicity' sect into noteables (not worth elaboration due to insignificance, but made a noteable for thoroughness)

2024-04-08T13:53:53Z

B12 Toxicity: Reworked 'B12 Toxicity' sect into noteables (not worth elaboration due to insignificance, but made a noteable for thoroughness)

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	It's commonly advised to persist with treatment until all symptoms have subsided, not merely until the B12 serum level surpasses 350 pmol/L (500 ng/L). Generally, measuring the serum B12 level during treatment is not meaningful as it becomes artificially elevated, potentially leading to misinterpretations, such as prematurely discontinuing treatment.		It's commonly advised to persist with treatment until all symptoms have subsided, not merely until the B12 serum level surpasses 350 pmol/L (500 ng/L). Generally, measuring the serum B12 level during treatment is not meaningful as it becomes artificially elevated, potentially leading to misinterpretations, such as prematurely discontinuing treatment.

	== B12 Toxicity ==		== Noteable Mentions ==

			=== B12 Toxicity ===

			B12 Toxicity occurs when the body has too much of the B12 mineral. Due to Vitamin B12s role in the body, toxicity is hard to achieve but it is possible. The most likely cause comes from unnecessary supplementation, as most people recieve adequate B12 from their diet.

			There have been no mentions of B12 toxicity causing brainfog within the community, most likely due to how difficult it is to 'overdose' on it.

	== See Also ==		== See Also ==

DefunctSprout: /* See Also */

2024-04-05T14:59:50Z

DefunctSprout: /* See Also */ Formatting

2024-04-05T14:59:34Z

DefunctSprout: /* See Also */ added source

2024-04-05T14:59:20Z

DefunctSprout: /* Nutritional Support */ formatting and removing repetitive source already mentioned in 'See Also'

2024-04-05T14:56:55Z

Nutritional Support: formatting and removing repetitive source already mentioned in 'See Also'

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	===Nutritional Support===		===Nutritional Support===

	* Folate: Ensure adequate folate intake of 1-5mg per day, either through diet or supplementation with bioavailable forms like methylfolate or folinic acid. High doses of B12 can induce folate deficiency symptoms, which requires careful management, especially in individuals with MTHFR mutations affecting folate processing.		* Folate: Ensure adequate folate intake of 1-5mg per day, either through diet or supplementation with bioavailable forms like methylfolate or folinic acid. High doses of B12 can induce folate deficiency symptoms, which requires careful management, especially in individuals with MTHFR mutations affecting folate processing.

	* Multivitamins: A high-quality multivitamin containing the full spectrum of B vitamins and trace minerals, including activated forms of these nutrients, is recommended. A product like Thorne's Basic Nutrients 2/Day is a solid choice.		* Multivitamins: A high-quality multivitamin containing the full spectrum of B vitamins and trace minerals, including activated forms of these nutrients, is recommended. A product like Thorne's Basic Nutrients 2/Day is a solid choice.

	* Trace Minerals: Consider a separate trace mineral complex to support Riboflavin and B12 metabolism, focusing on Selenium, Iodine, and Molybdenum. Molybdenum, often absent in multivitamins, is crucial.		* Trace Minerals: Consider a separate trace mineral complex to support Riboflavin and B12 metabolism, focusing on Selenium, Iodine, and Molybdenum. Molybdenum, often absent in multivitamins, is crucial.

	* Vitamin D3: Given the connection between vitamin D deficiency and B vitamin dysfunction, supplementing of vitamin D3 may be beneficial. Monitor electrolyte levels, as vitamin D can deplete them.		* Vitamin D3: Given the connection between vitamin D deficiency and B vitamin dysfunction, supplementing of vitamin D3 may be beneficial. Monitor electrolyte levels, as vitamin D can deplete them.

	* Magnesium and Potassium: Adequate daily intake of magnesium (400-600 mg, avoiding oxide forms) is crucial. The same goes for potassium, which requires daily replenishment. The Recommended Daily Allowance for potassium should be followed, ideally obtained through a mixture of diet and supplements. Considering the risk of hyperkalemia, especially in those with renal issues, monitoring and moderation are key. An electrolyte drink mix might offer a balanced approach to maintaining electrolyte levels.		* Magnesium and Potassium: Adequate daily intake of magnesium (400-600 mg, avoiding oxide forms) is crucial. The same goes for potassium, which requires daily replenishment. The Recommended Daily Allowance for potassium should be followed, ideally obtained through a mixture of diet and supplements. Considering the risk of hyperkalemia, especially in those with renal issues, monitoring and moderation are key. An electrolyte drink mix might offer a balanced approach to maintaining electrolyte levels.

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	It's commonly advised to persist with treatment until all symptoms have subsided, not merely until the B12 serum level surpasses 350 pmol/L (500 ng/L). Generally, measuring the serum B12 level during treatment is not meaningful as it becomes artificially elevated, potentially leading to misinterpretations, such as prematurely discontinuing treatment.		It's commonly advised to persist with treatment until all symptoms have subsided, not merely until the B12 serum level surpasses 350 pmol/L (500 ng/L). Generally, measuring the serum B12 level during treatment is not meaningful as it becomes artificially elevated, potentially leading to misinterpretations, such as prematurely discontinuing treatment.

	For more detailed information and discussions, you can visit the reddit r/b12_deficiency community and explore their comprehensive guide to B12 deficiency at: https://www.reddit.com/r/B12_Deficiency/wiki/index/

	== B12 Toxicity ==		== B12 Toxicity ==

DefunctSprout: Minor grammatical error

2024-04-05T14:54:39Z

Minor grammatical error

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	Vitamin B12 is an essential vitamin that binds to the protein in foods we eat. It is needed to form red blood cells and DNA, and a key player in the function and development of brain and nerve cells.		Vitamin B12 is an essential vitamin that binds to the protein in foods we eat. It is needed to form red blood cells and DNA, and is a key player in the function and development of brain and nerve cells.

	== B12 Deficiency ==		== B12 Deficiency ==

DefunctSprout at 14:53, 5 April 2024

2024-04-05T14:53:50Z

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	One a Vitamin B12 deficiency has been accurately diagnosed, treatment can begin. The treatment approach depends on the underlying cause of the deficiency, as well as the severity of the symptoms and test results.		One a Vitamin B12 deficiency has been accurately diagnosed, treatment can begin. The treatment approach depends on the underlying cause of the deficiency, as well as the severity of the symptoms and test results.

	==== Injections ===		==== Injections ====
	For severe deficiencies or cases where absorption is hampered (e.g., due to gastrointestinal issues), Vitamin B12 injections are usually the first line of treatment. These injections bypass the digestive system and provide a direct, potent dose of B12. The frequency and duration of the treatment vary based on individual needs, ranging from daily to monthly injections.		For severe deficiencies or cases where absorption is hampered (e.g., due to gastrointestinal issues), Vitamin B12 injections are usually the first line of treatment. These injections bypass the digestive system and provide a direct, potent dose of B12. The frequency and duration of the treatment vary based on individual needs, ranging from daily to monthly injections.

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	* [https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]		* [https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]
	* [https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]		* [https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]
	* [https://pubmed.ncbi.nlm.nih.gov/31018715/ Vitamin B12 ~~toxicity case~~]		* [https://pubmed.ncbi.nlm.nih.gov/31018715/ Vitamin B12 Toxicity Case Report]

← Older revision		Revision as of 13:54, 8 April 2024
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	* [https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]		* [https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]
	* [https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]		* [https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]
			* [https://pubmed.ncbi.nlm.nih.gov/31018715/ Vitamin B12 toxicity case]

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	== See Also ==		== See Also ==

	[https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]		* [https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]
			* [https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]
	[https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]

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	[https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]		[https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]

	[https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]		[https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]

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	== See Also ==		== See Also ==

			[https://www.hsph.harvard.edu/nutritionsource/vitamin-b12/ Nutritional Information from Harvard]
	[https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]		[https://www.reddit.com/r/B12_Deficiency/wiki/index/ The B12 Guide from r/B12_Deficiency]